Leiomyosarcoma of the sigmoid colon with biorherapy
نویسندگان
چکیده
Background: Leiomyosarcoma (LMS) of sigmoid colon is an extremely rare neoplasm with poor prognosis, which is often misdiagnosed as colonic adenocarcinoma. The diagnosis of LMS depends on the pathology. The mitosis and the histological grade observation are important for diagnosis. Unlike gastrointestinal stromal tumor, c-KIT in LMS is negative, and immunohistochemistry examination is positive for SMA, desmin, EMA and vimentin. Case presentation: Here, we report a case of colonic LMS, with incompletely intestinal obstruction and hematochezia. Sigmoidoscopy showed a large intraluminal lesion in the sigmoid colon and the surface was irregular, showing as dark and red. Colon was almost occluded. The surgically resected sigmoid colon was detected by immunohistochemitry and diagnosed as LMS, and biotherapy was given to the patient after surgery. Conclusion: With appropriate diagnosis and treatment, the prognosis of LMS is still poor. For this patient, the follow-up is still undergoing.
منابع مشابه
Author's response to reviews Title: Leiomyosarcoma of sigmoid colon with multiple liver metastases and gastric cancer: case report
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